SignaCell™

How it works

The technology is based on biomimetic signal induction - transmitting signals that imitate natural intercellular signals, without releasing any chemical substances. The signaling biopolymers act as an active communicator that significantly enhances the natural signaling of microorganisms, cells, and crop plants.

Key mechanism

Biopolymers with neural network-inspired architecture generate coordinated biomimetic signals that are recognized by cells as authentic pro-proliferative communication. This high-fidelity mimicry of natural signals leads to synergistic activation of multiple pathways simultaneously, achieving 400-500% efficiency increase through exploitation of crosstalk phenomena in the cellular signaling network.

The technology is delivered as a biotechnological tool in the form of a biopolymer with a specifically designed structure and active surface, serving directly as a molecular machine in the processes. Depending on individual process parameters (density, temperature, pressure, mixing method, kinetics, retention times, etc.), an appropriately sized polymer is selected, proving the automation and technology delivery method. 

Pathways activated through biomimetic signal induction

Mammalian cells

Mammalian cells

PI3K/AKT/mTOR pathway

PI3K/AKT/mTOR pathway

Activated by mimicking growth factor signals

MAPK/ERK cascade

MAPK/ERK cascade

Induced by imitating mitogenic signals

cAMP/PKA pathway

cAMP/PKA pathway

Stimulated by mimicking natural hormonal signals

Wnt/β-catenin pathway

Wnt/β-catenin pathway

Activated by biomimicry of developmental signals

Mammalian cells

PI3K/AKT/mTOR pathway

Activated by mimicking growth factor signals

MAPK/ERK cascade

Induced by imitating mitogenic signals

cAMP/PKA pathway

Stimulated by mimicking natural hormonal signals

Wnt/β-catenin pathway

Activated by biomimicry of developmental signals

Microorganisms

Microorganisms

Quorum sensing

Quorum sensing

Enhancement through autoinducer signal mimicry

Two-component signaling systems

Two-component signaling systems

Activation by imitating environmental signals

Stress response pathways

Stress response pathways

Induction through biomimicry of adaptive signals

TOR-like systems

TOR-like systems

Stimulation by mimicking nutrient availability signals

Microorganisms

Quorum sensing

Enhancement through autoinducer signal mimicry

Two-component signaling systems

Activation by imitating environmental signals

Stress response pathways

Induction through biomimicry of adaptive signals

TOR-like systems

Stimulation by mimicking nutrient availability signals

Fungi

Fungi

Mechanosensory pathways

Direct response to topographic and mechanical signals

Two-component systems

Two-component systems

Sensory systems responding to physical environmental changes

MAPK stress pathways

MAPK stress pathways

Activated by environmental signals (HOG, CWI)

Fungal quorum sensing

Fungal quorum sensing

Enhancement of natural communication through signal mimicry

Cell wall sensory systems

Cell wall sensory systems

Recognition of microenvironmental changes

Ca2+ ion channels

Ca2+ ion channels

Responding to electrical and mechanical signals

Fungi

Mechanosensory pathways

Direct response to topographic and mechanical signals

Two-component systems

Sensory systems responding to physical environmental changes

MAPK stress pathways

Activated by environmental signals (HOG, CWI)

Fungal quorum sensing

Enhancement of natural communication through signal mimicry

Cell wall sensory systems

Recognition of microenvironmental changes

Ca2+ ion channels

Responding to electrical and mechanical signals

Plants

Mechanosensory pathways

Mechanosensory pathways

Touch, wind responses and mechanical signals (thigmotropism)

Gravitropic systems

Gravitropic systems

Sensory responses to spatial orientation changes

Mechanosensitive ion channels

Mechanosensitive ion channels

Direct response to physical signals

Ca2+ pathways

Ca2+ pathways

Secondary messengers activated by electrical signals

Root sensory systems

Root sensory systems

Recognition of soil environment changes

MAPK stresss cascades

MAPK stresss cascades

Activated by abiotic stress signals

Plants

Mechanosensory pathways

Touch, wind responses and mechanical signals (thigmotropism)

Gravitropic systems

Sensory responses to spatial orientation changes

Mechanosensitive ion channels

Direct response to physical signals

Ca2+ pathways

Secondary messengers activated by electrical signals

Root sensory systems

Recognition of soil environment changes

MAPK stresss cascades

Activated by abiotic stress signals

Eukaryotic cells

PI3K/AKT/mTOR pathway

Activated by mimicking growth factor signals

MAPK/ERK cascade

Induced by imitating mitogenic signals

cAMP/PKA pathway

Stimulated by mimicking natural hormonal signals

Wnt/β-catenin pathway

Activated by biomimicry of developmental signals

Eukaryotic cells

PI3K/AKT/mTOR pathway

Activated by mimicking growth factor signals

MAPK/ERK cascade

Induced by imitating mitogenic signals

cAMP/PKA pathway

Stimulated by mimicking natural hormonal signals

Wnt/β-catenin pathway

Activated by biomimicry of developmental signals

Microorganisms

Quorum sensing

Enhancement through autoinducer signal mimicry

Two-component signaling systems

Activation by imitating environmental signals

Stress response pathways

Induction through biomimicry of adaptive signals

TOR-like systems

Stimulation by mimicking nutrient availability signals

Microorganisms

Quorum sensing

Enhancement through autoinducer signal mimicry

Two-component signaling systems

Activation by imitating environmental signals

Stress response pathways

Induction through biomimicry of adaptive signals

TOR-like systems

Stimulation by mimicking nutrient availability signals

Fungi

Mechanosensory pathways

Direct response to topographic and mechanical signals

Two-component systems

Sensory systems responding to physical environmental changes

MAPK stress pathways

Activated by environmental signals (HOG, CWI)

Fungal quorum sensing

Enhancement of natural communication through signal mimicry

Cell wall sensory systems

Recognition of microenvironmental changes

Ca2+ ion channels

Responding to electrical and mechanical signals

Fungi

Mechanosensory pathways

Direct response to topographic and mechanical signals

Two-component systems

Sensory systems responding to physical environmental changes

MAPK stress pathways

Activated by environmental signals (HOG, CWI)

Fungal quorum sensing

Enhancement of natural communication through signal mimicry

Cell wall sensory systems

Recognition of microenvironmental changes

Ca2+ ion channels

Responding to electrical and mechanical signals

Plants

Mechanosensory pathways

Touch, wind responses and mechanical signals (thigmotropism)

Gravitropic systems

Sensory responses to spatial orientation changes

Mechanosensitive ion channels

Direct response to physical signals

Ca2+ pathways

Secondary messengers activated by electrical signals

Root sensory systems

Recognition of soil environment changes

MAPK stresss cascades

Activated by abiotic stress signals

Plants

Mechanosensory pathways

Touch, wind responses and mechanical signals (thigmotropism)

Gravitropic systems

Sensory responses to spatial orientation changes

Mechanosensitive ion channels

Direct response to physical signals

Ca2+ pathways

Secondary messengers activated by electrical signals

Root sensory systems

Recognition of soil environment changes

MAPK stresss cascades

Activated by abiotic stress signals

Core Benefits

Accelerated bioprocesses contribute to the overall efficiency of production, reducing the time required for biochemical reactions and process completion.

Higher cell multiplication rates result in more rapid growth of microorganisms, increasing biomass production and  higher yields in biotechnological applications.

Improved nutrient conversion enhances the efficiency with which microorganisms utilize available nutrients, optimizing growth conditions and maximizing output.

Increased end-product yields from bioreactor cultures are achieved through optimized process conditions, leading to more efficient production of desired bioproducts.

Faster qualitative and quantitative determinations of microorganisms of microorganisms enable more rapid analysis and monitoring, which is crucial for optimizing bioprocesses and ensuring product quality.

Enhanced identification of primary and secondary metabolites in post-reaction mixtures allows for more accurate tracking of product formation and byproduct production, facilitating better control over the overall bioprocess.

In crop plants, it promotes growth, enhances micronutrient uptake, reduces stress levels, and positively influences the natural soil microbiome.

Proven Results

Our technology has been extensively validated through research conducted at prestigious institutions, demonstrating significant improvements across various applications:

Studies conducted within the JSH Hamilton Laboratory at the University of Rzeszów observed a fivefold increase in bacterial colony growth demonstrating enhanced microbial proliferation under specific conditions.

Salmonella strain detection was achieved five times faster, with results available in just five hours compared to the standard 24-hour detection period, improving the efficiency of pathogen monitoring. 

Industrial algae cultivation saw a 60% increase in daily algae growth rates, leading to enhanced productivity in algae-based production systems. 

Research conducted by the Polish Academy of Sciences demonstrated that fibroblast cultures exhibited a twelvefold increase in cell colony size, and sustained vitality across seven passages.

The Medical University of Warsaw reported that the biomass of Lentinula edodes fungal strains increased 16-fold, with improved morphological structure, as reported by, highlighting advances in fungal cultivation.

Significant foam reduction was achieved in biological wastewater treatment processes, decreasing from 30% to 13%, as demonstrated by BioTreaT GmbH in collaboration with the University of Innsbruck, contributing to more efficient treatment operations.

Eukaryotic cells

PI3K/AKT/mTOR pathway

Activated by mimicking growth factor signals

MAPK/ERK cascade

Induced by imitating mitogenic signals

cAMP/PKA pathway

Stimulated by mimicking natural hormonal signals

Wnt/β-catenin pathway

Activated by biomimicry of developmental signals

Microorganisms

Quorum sensing

Enhancement through autoinducer signal mimicry

Two-component signaling systems

Activation by imitating environmental signals

Stress response pathways

Induction through biomimicry of adaptive signals

TOR-like systems

Stimulation by mimicking nutrient availability signals

Fungi

Mechanosensory pathways

Direct response to topographic and mechanical signals

Two-component systems

Sensory systems responding to physical environmental changes

MAPK stress pathways

Activated by environmental signals (HOG, CWI)

Fungal quorum sensing

Enhancement of natural communication through signal mimicry

Cell wall sensory systems

Recognition of microenvironmental changes

Ca2+ ion channels

Responding to electrical and mechanical signals

Plants

Mechanosensory pathways

Touch, wind responses and mechanical signals (thigmotropism)

Gravitropic systems

Sensory responses to spatial orientation changes

Mechanosensitive ion channels

Direct response to physical signals

Ca2+ pathways

Secondary messengers activated by electrical signals

Root sensory systems

Recognition of soil environment changes

MAPK stresss cascades

Activated by abiotic stress signals

Core Benefits

Accelerated bioprocesses contribute to the overall efficiency of production, reducing the time required for biochemical reactions and process completion.

Higher cell multiplication rates result in more rapid growth of microorganisms, increasing biomass production and  higher yields in biotechnological applications.

Improved nutrient conversion enhances the efficiency with which microorganisms utilize available nutrients, optimizing growth conditions and maximizing output.

Increased end-product yields from bioreactor cultures are achieved through optimized process conditions, leading to more efficient production of desired bioproducts.

Faster qualitative and quantitative determinations of microorganisms of microorganisms enable more rapid analysis and monitoring, which is crucial for optimizing bioprocesses and ensuring product quality.

Enhanced identification of primary and secondary metabolites in post-reaction mixtures allows for more accurate tracking of product formation and byproduct production, facilitating better control over the overall bioprocess.

In crop plants, it promotes growth, enhances micronutrient uptake, reduces stress levels, and positively influences the natural soil microbiome.

Proven Results

Our technology has been extensively validated through research conducted at prestigious institutions, demonstrating significant improvements across various applications:

Studies conducted within the JSH Hamilton Laboratory at the University of Rzeszów observed a fivefold increase in bacterial colony growth demonstrating enhanced microbial proliferation under specific conditions.

Salmonella strain detection was achieved five times faster, with results available in just five hours compared to the standard 24-hour detection period, improving the efficiency of pathogen monitoring. 

Industrial algae cultivation saw a 60% increase in daily algae growth rates, leading to enhanced productivity in algae-based production systems. 

Research conducted by the Polish Academy of Sciences demonstrated that fibroblast cultures exhibited a twelvefold increase in cell colony size, and sustained vitality across seven passages.

The Medical University of Warsaw reported that the biomass of Lentinula edodes fungal strains increased 16-fold, with improved morphological structure, as reported by, highlighting advances in fungal cultivation.

Significant foam reduction was achieved in biological wastewater treatment processes, decreasing from 30% to 13%, as demonstrated by BioTreaT GmbH in collaboration with the University of Innsbruck, contributing to more efficient treatment operations.

Overall Technical Implementation and Benefits

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

Universal Process Integration

Validated Technology Benefits Across Industries

Economic Impact

Environmental and Sustainability Benefits

Quality Assurance

Competitive Advantages

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